喹啉
抗细菌
化学
抗真菌
生物活性
药理学
药品
药物发现
组合化学
生物化学
体外
有机化学
生物
微生物学
医学
病理
结核分枝杆菌
肺结核
作者
S. M. Basavarajaiah,Raviraj S. Pattanashettar,Nagesh Gunavanthrao Yernale
标识
DOI:10.1016/j.bmc.2020.115973
摘要
Amongst heterocyclic compounds, quinoline is an advantaged scaffold that appears as a significant assembly motif for the development of new drug entities. Quinoline and its derivatives tested with diverse biological activity constitute an important class of compounds for new drug development. Therefore, many scientific communities have developed these compounds as intent structure and evaluated their biological activities. The present, review provides brief natural sources of quinoline and including a new extent of quinoline-based marketed drugs. This review also confers information about the biological activities of quinoline derivatives such as antibacterial, antifungal, antimycobacterial, antiviral, anti-protozoal, antimalarial, anticancer, cardiovascular, CNS effects, antioxidant, anticonvulsant, analgesic, anti-inflammatory, anthelmintic and miscellaneous activities.
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