双聚类
计算机科学
聚类分析
进化算法
数据挖掘
进化计算
表达式(计算机科学)
人口
微阵列分析技术
趋同(经济学)
排
模式识别(心理学)
人工智能
算法
基因
生物
基因表达
相关聚类
树冠聚类算法
遗传学
人口学
经济增长
社会学
经济
程序设计语言
数据库
作者
Qinghua Huang,Xianhai Huang,Zhoufan Kong,Xuelong Li,Dacheng Tao
标识
DOI:10.1109/tevc.2018.2884521
摘要
The analysis of gene expression data is useful for detecting the biological information of genes. Biclustering of microarray data has been proposed as a powerful computational tool to discover subsets of genes that exhibit consistent expression patterns along subsets of conditions. In this paper, we propose a novel biclustering algorithm called the bi-phase evolutionary biclustering algorithm. The first phase is for the evolution of rows and columns, and the other is for the evolution of biclusters. The interaction of the two phases ensures a reliable search direction and accelerates the convergence to good solutions. Furthermore, the population is initialized using a conventional hierarchical clustering strategy to discover bicluster seeds. We also developed a seed-based parallel implementation of evolutionary searching to search biclusters more comprehensively. The performance of the proposed algorithm is compared with several popular biclustering algorithms using synthetic datasets and real microarray datasets. The experimental results show that the algorithm demonstrates a significant improvement in discovering biclusters.
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