医学
哮喘
优势比
置信区间
内科学
流行病学
慢性阻塞性肺病
儿科
作者
June H. Lee,Tmirah Haselkorn,Larry Borish,Lawrence Rasouliyan,Bradley E. Chipps,Sally E. Wenzel
出处
期刊:Chest
[Elsevier]
日期:2007-12-01
卷期号:132 (6): 1882-1889
被引量:175
标识
DOI:10.1378/chest.07-0713
摘要
The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens study is among the largest to assess persistent airflow limitation and the first to evaluate a wide range of potential risk factors in high-risk patients with severe or difficult-to-treat asthma. A better understanding is needed regarding factors associated with persistent airway obstruction; this study was performed to determine demographic and clinical characteristics associated with persistent airflow limitation.Data from adult patients (>or= 18 years old) with severe or difficult-to-treat asthma were evaluated. Patients with COPD, obesity with a restrictive respiratory pattern, or a >or= 30 pack-year history of smoking were excluded. Patients with persistent airflow limitation (postbronchodilator FEV1/FVC ratio
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