医学
心肌梗塞
尿酸
内皮功能障碍
流行病学
内科学
心脏病学
疾病
病理生理学
氧化应激
炎症
叙述性评论
冠状动脉疾病
重症监护医学
作者
Atalay Demiray,Barış Afşar,Adrian Covic,Masanari Kuwabara,Charles J. Ferro,Miguel A. Lanaspa,Richard J. Johnson,Mehmet Kanbay
出处
期刊:Angiology
[SAGE]
日期:2021-04-27
卷期号:73 (1): 9-17
被引量:17
标识
DOI:10.1177/00033197211012546
摘要
Increased serum uric acid (SUA) levels have been associated with various pathologic processes such as increased oxidative stress, inflammation, and endothelial dysfunction. Thus, it is not surprising that increased SUA is associated with various adverse outcomes including cardiovascular (CV) diseases. Recent epidemiological evidence suggests that increased SUA may be related to acute myocardial infarction (AMI). Accumulating data also showed that elevated UA has pathophysiological role in the development of AMI. However, there are also studies showing that SUA is not related to the risk of AMI. In this narrative review, we summarized the recent literature data regarding SUA and AMI after providing some background information for the association between UA and coronary artery disease. Future studies will show whether decreasing SUA levels is beneficial for outcomes related to AMI and the optimum SUA levels for best outcomes in CV diseases.
科研通智能强力驱动
Strongly Powered by AbleSci AI