医学
四分位间距
病毒载量
巨细胞病毒
移植
造血细胞
内科学
造血干细胞移植
挽救疗法
回顾性队列研究
队列
病毒血症
人巨细胞病毒
胃肠病学
免疫学
病毒性疾病
病毒
疱疹病毒科
化疗
造血
干细胞
生物
遗传学
作者
Valentina Gutiérrez,Joseph Stanek,Monica I. Ardura,Eunkyung Song
摘要
Cytomegalovirus (CMV) contributes to morbidity and mortality in allogeneic hematopoietic cell transplantation (allo-HCT) recipients. Pre-emptive antiviral therapy (PET) reduces the incidence of CMV end-organ disease (EOD), though relevant viral thresholds to initiate PET remain undefined. We evaluated the impact of viral loads (VLs) at PET initiation on virologic and clinical outcomes following pediatric allo-HCT.
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