已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

Sarcopenic Obesity and Risk of Disability in Community-Dwelling Japanese Older Adults: A 5-Year Longitudinal Study

肌萎缩 肌萎缩性肥胖 医学 危险系数 肥胖 人口 纵向研究 老年学 比例危险模型 物理疗法 内科学 置信区间 环境卫生 病理
作者
Masanori Morikawa,Sang Yoon Lee,Keitaro Makino,Kenji Harada,Osamu Katayama,Kouki Tomida,Ryo Yamaguchi,Chiharu Nishijima,Kazuya Fujii,Yuka Misu,Mitsuhiro Katashima,Hiroyuki Shimada
出处
期刊:Journal of the American Medical Directors Association [Elsevier]
卷期号:24 (8): 1179-1184.e1 被引量:9
标识
DOI:10.1016/j.jamda.2023.03.008
摘要

Objectives Previous studies have indicated that sarcopenic obesity is a risk factor for disability onset. However, these studies had disparities in terms of criteria for sarcopenia, study design, or study population. No longitudinal study has investigated the effect of sarcopenic obesity on disability onset in an Asian population using the Asian Working Group for Sarcopenia 2019 criteria for sarcopenia definition. Herein, we aimed to investigate the longitudinal effect of sarcopenic obesity on disability onset in Japanese older adults and extend the generalizability of results to other populations. Design Longitudinal cohort study. Setting and Participants A total of 4197 Japanese older adults (mean age 74.6 ± 5.0 years, 54.2% women) formed our study population. Measurements Sarcopenia was identified using the Asian Working Group for Sarcopenia 2019 algorithm. Obesity was determined when body fat percentage was ≥25%, or when visceral fat content was ≥100 cm2 for either sex. Disability onset was defined as a new case of long-term care insurance system certification for 5 years from baseline. Missing values were managed with multi-imputation. Cox proportional hazard regression analysis was used with disability onset as dependent variable and group (nonsarcopenia/nonobesity as a reference, nonsarcopenia/obesity, sarcopenia/non-obesity, possible sarcopenia/obesity, possible sarcopenia/non-obesity, sarcopenic obesity) as explanatory variable, and was adjusted for potential confounding factors. Results When the nonsarcopenia/nonobesity group was used as the reference category, other groups such as possible-sarcopenia/nonobesity [hazard ratio (HR) 1.38, 95% confidential interval (95% CI) 1.29‒1.47, P < .028], possible-sarcopenia/obesity (HR 1.54, 95% CI 1.46‒1.62 P < .001), sarcopenia/nonobesity (HR 2.09, 95% CI 1.96‒2.23, P < .001), and sarcopenic obesity (HR 2.48, 95% CI 2.24‒2.75, P < .001) showed significantly increased HRs. Conclusions and Implications The risk of disability onset because of sarcopenic obesity was exceedingly higher compared with sarcopenia alone among community-dwelling older adults in Japan The health providers should consider assessing the co-existence of sarcopenia and obesity to screen for the risk of disability onset in the community-dwelling population.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
於芷波发布了新的文献求助10
刚刚
刚刚
刚刚
每天都要哈哈哈完成签到,获得积分20
刚刚
千城暮雪发布了新的文献求助10
1秒前
Luckovo完成签到 ,获得积分10
3秒前
顾矜应助Two-Capitals采纳,获得10
3秒前
3秒前
3秒前
lyy66964193完成签到,获得积分10
4秒前
4秒前
科研通AI2S应助橙子fy16_采纳,获得10
7秒前
小蘑菇应助linjinhualu采纳,获得10
7秒前
小美酱发布了新的文献求助10
8秒前
guard发布了新的文献求助10
8秒前
10秒前
samjoo发布了新的文献求助10
10秒前
shjyang完成签到,获得积分0
13秒前
13秒前
qingqing168完成签到,获得积分10
16秒前
17秒前
积极的香菇完成签到 ,获得积分10
17秒前
在水一方应助Jade采纳,获得10
19秒前
19秒前
蓝天发布了新的文献求助10
21秒前
生生不息完成签到,获得积分10
22秒前
wswddtd发布了新的文献求助10
23秒前
sunglow11完成签到,获得积分0
26秒前
離原完成签到,获得积分10
27秒前
完美世界应助小零食采纳,获得10
27秒前
27秒前
露露完成签到 ,获得积分10
28秒前
LSH完成签到 ,获得积分10
28秒前
30秒前
橘子日落发布了新的文献求助10
34秒前
Lucas应助小马驹采纳,获得10
40秒前
丘比特应助QQ采纳,获得10
40秒前
伶俐的觅儿完成签到,获得积分10
41秒前
41秒前
samjoo完成签到,获得积分10
43秒前
高分求助中
The ACS Guide to Scholarly Communication 2500
Microlepidoptera Palaearctica, Volumes 1 and 3 - 13 (12-Volume Set) [German] 1122
PraxisRatgeber Mantiden., faszinierende Lauerjäger. – Buch gebraucht kaufen 700
Mantiden - Faszinierende Lauerjäger – Buch gebraucht kaufen 700
Acute Care Physical Therapy 500
Ожившие листья и блуждающие цветы. Практическое руководство по содержанию богомолов [Alive leaves and wandering flowers. A practical guide for keeping praying mantises] 500
Development of a new synthetic process for the synthesis of (S)-methadone and (S)- and (R)-isomethadone as NMDA receptor antagonists for the treatment of depression 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3095061
求助须知:如何正确求助?哪些是违规求助? 2747028
关于积分的说明 7592325
捐赠科研通 2398494
什么是DOI,文献DOI怎么找? 1272568
科研通“疑难数据库(出版商)”最低求助积分说明 615390
版权声明 598906