赤藓糖醇
木糖醇
糖醇
多元醇
化学
吸收(声学)
食品科学
生物化学
色谱法
糖
发酵
材料科学
有机化学
复合材料
聚氨酯
作者
Valentine Bordier,Fabienne Teysseire,Frank Senner,Götz Schlotterbeck,Jürgen Drewe,Christoph Beglinger,Bettina K. Wölnerhanssen,Anne Christin Meyer‐Gerspach
摘要
The natural sweeteners erythritol and xylitol might be helpful to reduce sugar consumption and therefore prevent obesity and diabetes. The aim of the present study was to determine the absorption and metabolization into erythronate of different concentrations of erythritol and xylitol. Seventeen healthy lean participants received intragastric solutions of 10, 25, or 50 g erythritol or 7, 17, or 35 g xylitol on three study days in a randomized order. The study was double blinded with respect to the doses administered. We assessed plasma concentrations of erythritol, xylitol, and erythronate at fixed time intervals after administration with gas chromatography-mass spectrometry. We found: (i) a dose-dependent and saturable absorption of erythritol, (ii) a very low absorption of xylitol, (iii) a dose-dependent metabolization of erythritol into erythronate, and (iv) no metabolization of xylitol into erythronate. The implications of the metabolization of erythritol into erythronate for human health remain to be determined and more research in this area is needed.
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