胡杨
萜类
神经保护
生药学
植物
二萜
传统医学
杨柳科
生物
化学
木本植物
立体化学
生物活性
医学
药理学
体外
生物化学
作者
Yunyun Liu,Fu‐Ying Qin,Tian-Chang He,Yiping Xiong,Yong‐Ming Yan,Yong‐Xian Cheng
出处
期刊:Fitoterapia
[Elsevier]
日期:2020-03-19
卷期号:143: 104560-104560
被引量:7
标识
DOI:10.1016/j.fitote.2020.104560
摘要
Five new terpenoids including one new abietane diterpenoid (1), one new aromadendrane diterpenoid (6), two new norsesquiterpenoids (8 and 9), and a new cembrane-derived diterpenoid (12), together with seven known compounds were isolated from Populus euphratica resins. The structures of these new compounds, including their absolute configurations, were characterized by spectroscopic and computational methods. All the compounds except 8 were test for their neuroprotective activities. The result revealed that compounds 1, 7, and 10–12 display neuroprotective activities in glutamate-induced SH-SY5Y cells in a concentration-dependent manner.
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