Plasma exchange, a promising liver support system with still relevant uncertainties

1Liver ICU, Liver Unit, Hospital Clinic, University of Barcelona, IDIBAPS and CIBERehd, Spain 2EF Clif, EASL-CLIF Consortium, Barcelona, Spain 3Department of Hemotherapy and Hemostasis, Apheresis & Cellular Therapy Unit, ICMHO, Hospital Clínic de Barcelona, Barcelona, Spain, IDIBAPS, Barcelona, Spain. University of Barcelona, Barcelona, Spain Abbreviations: ACLF, acute-on-chronic liver failure; ALF, acute liver failure; LT, liver transplantation; PE, plasma exchange; RCT, randomized controlled trial. Correspondence Javier Fernandez, Liver Unit, Hospital Clínic, Villarroel 170, 08036, Barcelona, Spain. Email: [email protected]