Structural brain differences in the Alzheimer’s disease continuum: Insights into the heterogeneity from a large multi-site neuroimaging consortium

Neurodegenerative diseases require collaborative, multi-site research to comprehensively grasp their complex and diverse pathological progression, yet there is caution in aggregating global data due to data heterogeneity. The current study investigates brain structure across stages of Alzheimer's disease (AD), and how relationships vary across sources of heterogeneity.