Synthesis of Heteroatom Stereocenters by Enantioselective CH Functionalization

Abstract Enantioselective CH functionalization is one of the most straightforward and efficient approaches to access synthetically valuable chiral molecules. Only recently, transition metal‐catalyzed enantioselective CH functionalization has been explored to construct heteroatom stereocenters, providing molecules with heteroatom stereocenters that cannot be accessed otherwise. This article aims to provide a recent update toward the construction of heteroatom stereocenters through enantioselective CH functionalization including desymmetrization approach and resolution approach. The content is categorized according to the formed stereogenic atoms including P, Si, S‐stereocenters.