Effects of neoadjuvant chemotherapy (NAC) on tumor infiltrating lymphocytes (TIL) and PD-L1 expression in the SWOG S0800 clinical trial.
癌症研究
免疫疗法
肿瘤微环境
PD-L1
新辅助治疗
作者
Vasiliki Pelekanou,William E. Barlow,Marie-Kristin von Wahlde,Brad Wasserman,Ying-Chun Lo,Daniel F. Hayes,Gabriel N. Hortobagyi,Julie Gralow,Debu Tripathy,Robert B. Livingston,Peggy L. Porter,Zeina Nahleh,David L. Rimm,Lajos Pusztai
519Background: Higher baseline TILs and PD-L1 expression are associated with greater pathologic complete response (pCR) rates, but how chemotherapy affects these immune parameters is unknown. The g...
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