CpG站点
免疫疗法
癌症免疫疗法
炎症
癌症研究
医学
免疫系统
癌症
CpG寡核苷酸
材料科学
免疫学
抗体
生物
内科学
生物化学
DNA甲基化
基因表达
基因
作者
Chao Wang,Wujin Sun,Grace Wright,Andrew Z. Wang,Zhen Gu
标识
DOI:10.1002/adma.201506312
摘要
Inflammation-triggered combination delivery of anti-PD-1 antibody and CpG oligodeoxynucleotides (CpG ODNs) has been demonstrated to prevent cancer relapse utilizing postsurgical inflammatory response. The controlled release of anti-PD1 and CpG ODN by CpG DNA-based "nano-cocoons" can induce considerable immune response, which in turn significantly prolongs the survival time of mice. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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