Association Between Contact Lens Discomfort and Pre-lens Tear Film Kinetics

隐形眼镜 有机硅水凝胶 眼科 医学 镜头(地质) 人造眼泪 光学 物理
作者
Michel Guillon,Kathy Dumbleton,Panagiotis Theodoratos,Stéphanie Wong,Kishan Patel,Gaidig Banks,Trisha Patel
出处
期刊:Optometry and Vision Science [Lippincott Williams & Wilkins]
卷期号:93 (8): 881-891 被引量:42
标识
DOI:10.1097/opx.0000000000000866
摘要

The relationship between contact lens wettability and comfort has been extensively evaluated; however, a direct correlation between the characteristics of the pre-lens tear film and the symptoms associated with contact lens discomfort has yet to be established. In addition, there is relatively limited knowledge relating to the entire tear film kinetics during the inter-blink period in contact lens wearers. The purpose of this analysis was to identify the characteristics of the pre-lens tear film kinetics that may be associated with the symptoms of contact lens discomfort.The study population comprised 202 soft (hydrogel and silicone hydrogel) contact lens wearers attending pre-screening visits at the OTG-i research clinic. All participants completed the Ocular Surface Disease Index (OSDI) questionnaire and the tear film was quantified via post hoc, masked analysis of high definition digital Tearscope videos recorded at the visit. The tear film kinetics of the least symptomatic wearers (OSDI lowest quintile scores, n = 45) were compared to the tear film kinetics of the most symptomatic wearers (OSDI highest quintile scores, n = 43). The hypothesis tested was that the tear film kinetics of asymptomatic wearers were better than tear film kinetics of symptomatic wearers.The distribution of lens types worn was as follows: Daily Disposable 46.5%, 1-Month Replacement 39.6%, and 2-Week Replacement 13.6%. 48.2% of lenses were silicone hydrogel and 51.8% hydrogel. Symptomatic wearers had a shorter break-up time (4.7 s vs. 6.0 s; p = 0.003), lesser surface coverage by the tear film during the interblink period (95.1% vs. 98.5%; p < 0.001) and greater surface exposure at the time of the blink (9.4% vs. 3.9%; p = 0.001).The current study demonstrated that the tear film kinetics of asymptomatic and symptomatic contact lens wearers were different, the findings supporting the hypothesis of poorer tear film kinetics for symptomatic than asymptomatic wearers in a general contact lens wearing population.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
3秒前
3秒前
科研通AI5应助jingxian采纳,获得10
3秒前
lukawa发布了新的文献求助10
3秒前
yarazhang发布了新的文献求助10
4秒前
zhangkexin发布了新的文献求助10
4秒前
5秒前
5秒前
重要无招发布了新的文献求助10
7秒前
10秒前
10秒前
辛夷发布了新的文献求助10
11秒前
充电宝应助来来采纳,获得10
11秒前
重要无招完成签到,获得积分10
11秒前
Hanson完成签到,获得积分10
12秒前
13秒前
zhangkexin完成签到,获得积分10
13秒前
cndxh完成签到 ,获得积分10
14秒前
14秒前
14秒前
Akim应助哭泣的金鱼采纳,获得10
14秒前
合适橘完成签到,获得积分10
15秒前
聪明山芙完成签到,获得积分10
15秒前
慵懒芙芙完成签到 ,获得积分10
15秒前
jinmuna发布了新的文献求助20
15秒前
基金中中中完成签到,获得积分10
16秒前
16秒前
沈万熙发布了新的文献求助10
17秒前
乐乐发布了新的文献求助10
19秒前
20秒前
绵羊座鸭梨完成签到 ,获得积分10
21秒前
jingxian发布了新的文献求助10
24秒前
25秒前
深情安青应助斯文念波采纳,获得10
26秒前
充电宝应助清仔采纳,获得10
28秒前
bkagyin应助乐乐采纳,获得10
28秒前
lili完成签到 ,获得积分10
28秒前
29秒前
一一yi完成签到,获得积分10
30秒前
金鱼完成签到,获得积分10
31秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989589
求助须知:如何正确求助?哪些是违规求助? 3531795
关于积分的说明 11254881
捐赠科研通 3270329
什么是DOI,文献DOI怎么找? 1804966
邀请新用户注册赠送积分活动 882136
科研通“疑难数据库(出版商)”最低求助积分说明 809176