疟疾
生物
寄生虫寄主
伯氏疟原虫
疟原虫(生命周期)
转录组
地图集(解剖学)
恶性疟原虫
载体(分子生物学)
进化生物学
计算生物学
基因
遗传学
基因表达
免疫学
计算机科学
古生物学
万维网
重组DNA
作者
Virginia M. Howick,Andrew Russell,Tallulah Andrews,Haynes Heaton,Adam J. Reid,Kedar Nath Natarajan,Hellen Butungi,Tom Metcalf,Lisa Verzier,Julian C. Rayner,Matthew Berriman,Jeremy K. Herren,Oliver Billker,Martin Hemberg,Arthur M. Talman,Mara Lawniczak
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2019-08-23
卷期号:365 (6455)
被引量:219
标识
DOI:10.1126/science.aaw2619
摘要
Malaria parasites adopt a remarkable variety of morphological life stages as they transition through multiple mammalian host and mosquito vector environments. We profiled the single-cell transcriptomes of thousands of individual parasites, deriving the first high-resolution transcriptional atlas of the entire
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