肌萎缩侧索硬化
失智症
萎缩
运动皮层
神经科学
运动功能
医学
心理学
C9orf72
痴呆
疾病
物理医学与康复
内科学
刺激
作者
Rebekah M. Ahmed,Matthew C. Kiernan
出处
期刊:Neurology
[Ovid Technologies (Wolters Kluwer)]
日期:2021-06-07
卷期号:96 (23): 1103-1104
标识
DOI:10.1212/wnl.0000000000012073
摘要
We thank Dr. Abe for his interest in our study1 that investigated survival in patients with amyotrophic lateral sclerosis-frontotemporal dementia (ALS-FTD). Specific comparison of motor and cognitive presentations in ALS-FTD established that patients with a motor onset of their disease had reduced survival—which was associated with increased motor cortex atrophy—suggesting that survival may be mediated by motor function and other critical physiologic aspects.
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