Nanotechnology Based Drug Delivery for HIV-AIDS Treatment

纳米载体 药品 药物输送 药剂学 药理学 生物利用度 医学 纳米技术 人类免疫缺陷病毒(HIV) 靶向给药 纳米医学 脂质体 不利影响 纳米颗粒 材料科学 病毒学
作者
Inampudi Sailaja,Manoj Kumar Baghel,Ivvala Anand Shaker
出处
期刊:IntechOpen eBooks [IntechOpen]
被引量:4
标识
DOI:10.5772/intechopen.97736
摘要

One of the biggest challenges of the world in this 21st century is to cure HIV-AIDS. In Present scenario different antiviral drugs are available in the market to reduce the worse condition and manage improved survival rate. These drugs are manageable but their bioavailability, lower permeability and poor half life of the drugs have limitations. If the drug is preferred in higher dosage in AIDS patients, the drug leads to toxicity and adverse effects to patients and increase resistant against HIV & if the drug is preferred in lower dose along with nano carriers it will reach the target area for beneficial effect, therefore drugs Lacking of Knowledge in Potent Drug delivery systems is due to instability, chemical degradation and tissue barrier difficulties are reasons to reach drug target successfully. In this scenario Nanotechnology based antiretroviral drugs delivery holds drug and will provide to cure AIDS. Nanotechnology based deliver system Nanocarriers like Liposomes, dendrimers, Nanoparticles, Polymeric Micelles, Nanovesicles, Nanoemulsion provide the way to deliver drug to targeting tissue. Nanobased carriers revolutionized the field of Pharmaceutics and Pharmaco Kinetic’s in target drug delivery. The present study depicts nano based ARV drug provides increase efficiency with less adverse effects to control HIV. Like same way we can provide and increase nanobased drug delivery capacity to other available HIV drugs.
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