Metal–Organic Framework (MOF)‐Based Drug/Cargo Delivery and Cancer Therapy

Advanced MaterialsVolume 29, Issue 23 1606134 Review Metal–Organic Framework (MOF)-Based Drug/Cargo Delivery and Cancer Therapy Ming-Xue Wu, Ming-Xue Wu International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun, 130012 ChinaSearch for more papers by this authorYing-Wei Yang, Corresponding Author Ying-Wei Yang ywyang@jlu.edu.cn International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun, 130012 ChinaE-mail: ywyang@jlu.edu.cnSearch for more papers by this author Ming-Xue Wu, Ming-Xue Wu International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun, 130012 ChinaSearch for more papers by this authorYing-Wei Yang, Corresponding Author Ying-Wei Yang ywyang@jlu.edu.cn International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun, 130012 ChinaE-mail: ywyang@jlu.edu.cnSearch for more papers by this author First published: 29 March 2017 https://doi.org/10.1002/adma.201606134Citations: 1,308Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Metal–organic frameworks (MOFs)—an emerging class of hybrid porous materials built from metal ions or clusters bridged by organic linkers—have attracted increasing attention in recent years. The superior properties of MOFs, such as well-defined pore aperture, tailorable composition and structure, tunable size, versatile functionality, high agent loading, and improved biocompatibility, make them promising candidates as drug delivery hosts. Furthermore, scientists have made remarkable achievements in the field of nanomedical applications of MOFs, owing to their facile synthesis on the nanoscale and alternative functionalization via inclusion and surface chemistry. A brief introduction to the applications of MOFs in controlled drug/cargo delivery and cancer therapy that have been reported in recent years is provided here. Citing Literature Volume29, Issue23June 20, 20171606134 RelatedInformation