荧光
化学
检出限
分子内力
取代基
光化学
荧光团
香豆素
氰化物
质子核磁共振
硫化氢
分析化学(期刊)
硫黄
有机化学
色谱法
物理
量子力学
作者
Lingliang Long,Lin Wang,Yanjun Wu,Aihua Gong,Zulin Da,Chi Zhang,Zhixiang Han
标识
DOI:10.1002/asia.201402765
摘要
Abstract Herein, two compounds ( 1 a and 1 b ) were rationally constructed as novel reaction‐based fluorescent probes for CN − by making use of the electron‐withdrawing ability of the cyano group that was formed from the sensing reaction. Notably, this design strategy was first employed for the development of fluorescent CN − probes. The experimental details showed that probe 1 a exhibited a fluorescence turn‐on response to CN − , whereas other anions, biological thiols, and hydrogen sulfide gave almost no interference. The detection limit of probe 1 a for CN − was found to be 0.12 μ M . The sensing reaction product of 1 a with CN − was characterized by NMR spectroscopy and mass spectrometry. TD‐DFT calculations demonstrated that the formed cyano group drives the intramolecular charge transfer (ICT) process from coumarin dye to the cyano group and thus the original strong ICT from the coumarin dye to the 3‐position pyridyl vinyl ketone substituent is weakened, which results in recovery of coumarin fluorescence. The practical utility of 1 a was also examined. By fabricating paper strips, probe 1 a can be used as a simple tool to detect CN − in field measurements. Moreover, probe 1 a has been successfully applied for quantitative detection of endogenous CN − from cassava root.
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