亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Uveitis is associated with hypertension and atherosclerosis in patients with ankylosing spondylitis: A cross-sectional study

医学 强直性脊柱炎 葡萄膜炎 内科学 巴斯菲 优势比 脊柱炎 疾病 家族史 横断面研究 逻辑回归 巴斯代人 眼科 病理 银屑病性关节炎
作者
Inger Jorid Berg,Anne Grete Semb,Désirée van der Heijde,Tore K Kvien,Jonny Hisdal,Inge Christoffer Olsen,Hanne Dagfinrud,Sella Aarrestad Provan
出处
期刊:Seminars in Arthritis and Rheumatism [Elsevier BV]
卷期号:44 (3): 309-313 被引量:21
标识
DOI:10.1016/j.semarthrit.2014.05.017
摘要

Uveitis is the most common extra-articular manifestation in patients with ankylosing spondylitis (AS), but the literature describing AS patients with a history of uveitis is limited. The objective was to examine if a history of uveitis in patients with AS is associated with increased disease activity and functional impairment and to investigate whether uveitis is associated with an increased frequency of cardiovascular comorbidities, defined here as hypertension and atherosclerosis.Data were recorded cross-sectionally through patient interviews, blood samples, clinical examination, and questionnaires. Carotid plaques were identified by ultrasonography. AS disease activity and function were compared across categories of uveitis using ANCOVA analyses. Associations between uveitis and hypertension and atherosclerosis [atherosclerotic cardiovascular disease (CVD) and/or carotid plaque] were analyzed in multivariate logistic regression models.Of 159 patients with AS (61.6% male, mean age 50.5 years), 84 (52.8%) had experienced one or more episodes of uveitis. AS disease activity was higher in patients with a history of uveitis, statistically significant for functional impairment [Bath AS Functional Index (BASFI)] [mean difference (95% CI)] lnBASFI = 0.2 (0.0-0.3), p = 0.05. Patients with uveitis had an increased odds ratio [OR (95% CI)] for hypertension [3.29 (1.29-8.41), p = 0.01] and atherosclerosis [2.57 (1.15-5.72), p = 0.02].AS patients with a history of uveitis had non-significantly higher disease activity and significantly higher functional impairment. A history of uveitis was associated with hypertension as well as atherosclerosis. These results may be important in identifying AS patients with elevated risk of CVD but should be confirmed in longitudinal cohorts.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
hgl完成签到,获得积分10
20秒前
29秒前
科研通AI2S应助科研通管家采纳,获得10
37秒前
37秒前
华仔应助精明晓刚采纳,获得10
58秒前
1分钟前
1分钟前
精明晓刚发布了新的文献求助10
1分钟前
糖伯虎完成签到 ,获得积分10
2分钟前
在水一方应助科研通管家采纳,获得10
2分钟前
光合作用完成签到,获得积分10
2分钟前
3分钟前
精明晓刚发布了新的文献求助10
3分钟前
精明晓刚完成签到,获得积分10
3分钟前
4分钟前
搜集达人应助kangkang采纳,获得10
4分钟前
英姑应助科研通管家采纳,获得10
4分钟前
kangkang完成签到,获得积分20
4分钟前
5分钟前
刘紫媛发布了新的文献求助10
5分钟前
故意的冰淇淋完成签到 ,获得积分10
5分钟前
刘紫媛完成签到,获得积分20
5分钟前
Lucas应助Dave采纳,获得10
5分钟前
刘紫媛关注了科研通微信公众号
5分钟前
6分钟前
Akitten发布了新的文献求助10
6分钟前
草木完成签到 ,获得积分20
6分钟前
完美世界应助科研通管家采纳,获得10
6分钟前
领导范儿应助科研通管家采纳,获得10
6分钟前
Orange应助Boren采纳,获得10
7分钟前
7分钟前
Boren发布了新的文献求助10
7分钟前
大个应助Boren采纳,获得10
7分钟前
Raunio完成签到,获得积分10
7分钟前
Akitten发布了新的文献求助10
7分钟前
完美世界应助lhy采纳,获得10
8分钟前
科研通AI2S应助科研通管家采纳,获得10
8分钟前
8分钟前
8分钟前
8分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990332
求助须知:如何正确求助?哪些是违规求助? 3532146
关于积分的说明 11256483
捐赠科研通 3271042
什么是DOI,文献DOI怎么找? 1805207
邀请新用户注册赠送积分活动 882302
科研通“疑难数据库(出版商)”最低求助积分说明 809234