医学
甲基强的松龙
减压
视力
外科
视神经
回顾性队列研究
麻醉
眼科
作者
Wen-Chi Yang,Chien-Tzung Chen,Pei-Kwei Tsay,Glenda H. De Villa,Yueh-Ju Tsai,Yu-Ray Chen
出处
期刊:Annals of Plastic Surgery
[Ovid Technologies (Wolters Kluwer)]
日期:2004-01-01
卷期号:52 (1): 36-42
被引量:61
标识
DOI:10.1097/01.sap.0000096442.82059.6d
摘要
In Brief This study was performed to identify factors that can affect the final outcome and to recognize the proper management for patients with traumatic optic neuropathy (TON). This retrospective study included 42 consecutive patients with TON after maxillofacial trauma. Megadose methylprednisolone was administered to all patients during the first 3 days after diagnosis. Twenty-four patients received treatment with megadose steroids combined with optic nerve decompression and the remaining 18 with megadose methylprednisolone alone. Initial visual acuity (IVA) was the statistically significant factor affecting the outcome of TON (P = 0.006 for improvement rate). Patients treated within 7 days after injury had a better improvement degree, P = 0.056. Patients in a surgical group with an IVA of no light perception (NLP) had a better improvement rate and degree (31.3%; 59.34 ± 22.18%) than those in nonsurgical group (0%, 0%; P = 0.272). Initial visual acuity is the critical factor that affects the outcome of TON. Surgical optic nerve decompression is considerable in maxillofacial trauma patients with an IVA of NLP. A retrospective comparison study of 42 patients with traumatic optic neuropathy showed that megadose methylprednisolone plus optic nerve decompression resulted in better visual improvement rate (31.3%) and degree (59.3%) than methylprednisolone alone (0%) when no light perception previously existed. Surgical treatment within seven days of injury was associated with a more favorable result.
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