In persons aged ≥45 y, the mt-sRNA test had 94% sensitivity for colorectal cancer and 46% for advanced adenomas

ACP Journal Club6 February 2024In persons aged ≥45 y, the mt-sRNA test had 94% sensitivity for colorectal cancer and 46% for advanced adenomasHarvey J. Murff, MD, MPHHarvey J. Murff, MD, MPHVanderbilt University Medical Center, Nashville, Tennessee, USA (H.J.M.)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/J23-0114 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationBarnell EK, Wurtzler EM, La Rocca J, et al. Multitarget stool RNA test for colorectal cancer screening. JAMA. 2023;330:1760-1768. https://pubmed.ncbi.nlm.nih.gov/37870871Clinical Impact RatingsGIM/FP/GP: Gastroenterology: References1. US Preventive Services Task Force; Davidson KW, Barry MJ, Mangione CM, et al. Screening for colorectal cancer: US Preventive Services Task Force recommendation statement. JAMA. 2021;325:1965-1977. [PMID: 34003218] Google Scholar2. Fisher DA, Princic N, Miller-Wilson LA, et al. Utilization of a colorectal cancer screening test among individuals with average risk. JAMA Netw Open. 2021;4:e2122269. [PMID: 34473259] Google Scholar3. Allen CJ, Bloom N, Rothka M, et al. Comprehensive cost implications of commercially available noninvasive colorectal cancer screening modalities. J Am Coll Surg. 2023;237:465-472. [PMID: 37219020] Google Scholar Author, Article, and Disclosure InformationAuthors: Harvey J. Murff, MD, MPHAffiliations: Vanderbilt University Medical Center, Nashville, Tennessee, USA (H.J.M.)Disclosures: The commentator has reported no disclosures of interest. The form can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=J23-0114.This article was published at Annals.org on 6 February 2024.ACP Journal Club is editorially independent from Annals of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Latest Keywords Adenomas Cancer detection and diagnosis Cancer screening Colonoscopy Colorectal cancer Fecal immunochemical test Genetic testing Lesions RNA Specificity ePublished: 6 February 2024 Copyright & PermissionsCopyright © 2024 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...