癫痫
迷走神经电刺激
神经调节
医学
胼胝体切开术
抗药性癫痫
不利影响
癫痫外科
发作类型
重症监护医学
刺激
迷走神经
精神科
内科学
作者
Ali A. Asadi‐Pooya,Francesco Brigo,Simona Lattanzi,Ingmar Blümcke
出处
期刊:The Lancet
[Elsevier]
日期:2023-07-01
卷期号:402 (10399): 412-424
被引量:59
标识
DOI:10.1016/s0140-6736(23)01048-6
摘要
Epilepsy is a common medical condition that affects people of all ages, races, social classes, and geographical regions. Diagnosis of epilepsy remains clinical, and ancillary investigations (electroencephalography, imaging, etc) are of aid to determine the type, cause, and prognosis. Antiseizure medications represent the mainstay of epilepsy treatment: they aim to suppress seizures without adverse events, but they do not affect the underlying predisposition to generate seizures. Currently available antiseizure medications are effective in around two-thirds of patients with epilepsy. Neurosurgical resection is an effective strategy to reach seizure control in selected individuals with drug-resistant focal epilepsy. Non-pharmacological treatments such as palliative surgery (eg, corpus callosotomy), neuromodulation techniques (eg, vagus nerve stimulation), and dietary interventions represent therapeutic options for patients with drug-resistant epilepsy who are not suitable for resective brain surgery.
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