Thermally Drawn-Based Microtubule Soft Continuum Robot for Cardiovascular Intervention

机器人 计算机科学 材料科学 模拟 生物医学工程 人工智能 医学
作者
Xufeng Wang,Wei Liu,Qinzhou Luo,Ligang Yao,Fanan Wei
出处
期刊:ACS Applied Materials & Interfaces [American Chemical Society]
卷期号:16 (23): 29783-29792
标识
DOI:10.1021/acsami.4c03885
摘要

Cardiovascular disease is becoming the leading cause of human mortality. In order to address this, flexible continuum robots have emerged as a promising solution for miniaturizing and automating vascular interventional equipment for diagnosing and treating cardiovascular diseases. However, existing continuum robots used for vascular intervention face challenges such as large cross-sectional sizes, inadequate driving force, and lack of navigation control, preventing them from accessing cerebral blood vessels or capillaries for medical procedures. Additionally, the complex manufacturing process and high cost of soft continuum robots hinder their widespread clinical application. In this study, we propose a thermally drawn-based microtubule soft continuum robot that overcomes these limitations. The proposed robot has cross-sectional dimensions several orders of magnitude smaller than the smallest commercially available conduits, and it can be manufactured without any length restrictions. By utilizing a driving strategy based on liquid kinetic energy advancement and external magnetic field for steering, the robot can easily navigate within blood vessels and accurately reach the site of the lesion. This innovation holds the potential to achieve controlled navigation of the robot throughout the entire blood vessel, enabling in situ diagnosis and treatment of cardiovascular diseases.
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