生物
发病机制
螺杆菌
幽门螺杆菌
病菌
胃炎
微生物学
疾病
细菌
消化性溃疡
炎症
慢性胃炎
胃粘膜
免疫学
胃
遗传学
胃肠病学
病理
医学
生物化学
作者
Thomas G. Blanchard,John G. Nedrud
标识
DOI:10.1002/9780471729259.mc08b01s24
摘要
Helicobacter species are Gram-negative bacteria that colonize the gastric or intestinal mucosa of many mammalian and avian hosts and induce histologic inflammation. The association of H. pylori with gastritis, peptic ulcer disease, and gastric cancers makes it a significant human pathogen. Animal models for these diseases are being used to explore the pathogenesis of H. pylori infection and in vaccine development (UNIT ). Both bacterial and host factors contribute to Helicobacter pathogenesis, and therefore the microbiology is very important. This unit describes how to culture the most commonly used gastric Helicobacter species, H. pylori, H. mustelae, and H. felis.
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