Retinal Vessel Segmentation by A Transformer-U-Net Hybrid Model with Dual-Path Decoder

This paper introduces an effective and efficient framework for retinal vessel segmentation. First, we design a Transformer-CNN hybrid model in which a Transformer module is inserted inside the U-Net to capture long-range interactions. Second, we design a dual-path decoder in the U-Net framework, which contains two decoding paths for multi-task outputs. Specifically, we train the extra decoder to predict vessel skeletons as an auxiliary task which helps the model learn balanced features. The proposed framework, named as TSNet, not only achieves good performances in a fully supervised learning manner but also enables a rough skeleton annotation process. The annotators only need to roughly delineate vessel skeletons instead of giving precise pixel-wise vessel annotations. To learn with rough skeleton annotations plus a few precise vessel annotations, we propose a skeleton semi-supervised learning scheme. We adopt a mean teacher model to produce pseudo vessel annotations and conduct annotation correction for roughly labeled skeletons annotations. This learning scheme can achieve promising performance with fewer annotation efforts. We have evaluated TSNet through extensive experiments on five benchmarking datasets. Experimental results show that TSNet yields state-of-the-art performances on retinal vessel segmentation and provides an efficient training scheme in practice.