MP40-03 SIGNIFICANCE OF RENAL PELVIS URINE GRAM STAIN, SYSTEMIC INFLAMMATION INDEX, WHITE BLOOD CELL RATIOS AND GUY STONE SCORE IN PREDICTING POST OPERATIVE FEVER AFTER mPCNL: A PROSPECTIVE OBSERVATIONAL STUDY

You have accessJournal of UrologyStone Disease: Epidemiology & Evaluation I (MP40)1 May 2024MP40-03 SIGNIFICANCE OF RENAL PELVIS URINE GRAM STAIN, SYSTEMIC INFLAMMATION INDEX, WHITE BLOOD CELL RATIOS AND GUY STONE SCORE IN PREDICTING POST OPERATIVE FEVER AFTER mPCNL: A PROSPECTIVE OBSERVATIONAL STUDY Jessie L. Harina, Albert T. Aquino, Juan Godofredo R. Bardelosa, Tomas Mario A. Yanga, and Adrian E. Guiang Jessie L. HarinaJessie L. Harina , Albert T. AquinoAlbert T. Aquino , Juan Godofredo R. BardelosaJuan Godofredo R. Bardelosa , Tomas Mario A. YangaTomas Mario A. Yanga , and Adrian E. GuiangAdrian E. Guiang View All Author Informationhttps://doi.org/10.1097/01.JU.0001008788.18007.3f.03AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Despite pre-procedural urine culture negativity or pathogen-specific treatment, post-PCNL infectious complications still occur. The European Association of Urology strongly recommends taking a stone culture or urine culture directly from the renal pelvis at time of PCNL, if possible. Recent studies have cited incongruencies between negative pre-operative midstream urine cultures and intra-operative renal pelvis urine and stone culture results, ultimately correlating with post-operative infectious complications. As such, growing research has focused on determining novel biomarkers that may predict post-procedural infectious complications in stone surgery. METHODS: This is a prospective observational study. We had a total of 96 patients aged 18-60 with a pre-operative non-contrast CT scan and a complete blood count who underwent mPCNL . The Renal pelvis urine gram stain (RPUGS), Systemic Inflammation Index (SII), White blood cell ratios (NLR, PLR, and LMR) and Guy Stone Score (GSS) was determined and were interpreted if these factors could predict post-operative fever. RESULTS: RPUGS, SII, and GSS was used to predict post-operative fever and showed an overall accuracy of 71.9%, 75% and 58.3% respectively. Among the white blood cell indices, NLR and PLR had an overall accuracy of 66.7% and 62.5% respectively. All factors show significant discriminatory ability between patients with and without post-operative fever. CONCLUSIONS: RPUGS, SII, NLR, PLR and GSS are early, useful, independent, and cost-effective predictors of intraoperative bacterial status, systemic inflammation and post operative fever, which can enable the surgeon to avoid more serious adverse infectious complications of mPCNL thru early aggressive empiric anti-biotherapy. Source of Funding: All expenses for imaging, laboratories and operating room fees were shouldered by the national health insurance and the tertiary government hospital © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e663 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Jessie L. Harina More articles by this author Albert T. Aquino More articles by this author Juan Godofredo R. Bardelosa More articles by this author Tomas Mario A. Yanga More articles by this author Adrian E. Guiang More articles by this author Expand All Advertisement PDF downloadLoading ...