Although neighborhood context is a well-recognized factor in the well-being of children and families, little systematic research exists to guide inquiries into the intersection of neighborhood social processes and child and family well-being. Moreover, despite the increased popularity of neighborhood effects research over the last several decades, crucial questions around the debate on how to align research findings with tangible experiences for children and families remain open. This article reviews selected studies that linked neighborhood factors to specific domains of child and family well-being: parenting, safety, health, and educational outcomes. By focusing on neighborliness, a particular form of neighboring, the study aims to shift the focus from macrolevel indicators of neighborhood context, to a more dynamic set of attributes that characterize neighborhood life, with the hope of inspiring others to build upon the findings and begin to translate the conclusions to meaningful policies and programs. (PsycInfo Database Record (c) 2021 APA, all rights reserved).