Congenital penile pathology is associated with abnormal development of the dartos muscle: a prospective study of primary penile surgery at a tertiary referral center.

作者
Anne-Françoise Spinoit,C. Van Praet,Luitzen Albert Groen,E. Van Laecke,Marleen Praet,Piet Hoebeke
出处
期刊:The Journal of Urology [Lippincott Williams & Wilkins]
卷期号:193 (5): 1620-1624 被引量:19
标识
DOI:10.1016/j.juro.2014.10.090
摘要

Purpose: Pathophysiological mechanisms leading to chordee in patients with hypospadias and to the hidden state of buried penis in the prepubic fat remain unclear. Resection of dartos tissue usually makes the penis straight in patients with hypospadias and corrects it in those with buried penis, suggesting a common pathophysiology related to dartos tissue.Materials and Methods: Tissue samples from 113 children undergoing primary penile surgery for hypospadias (94 patients), epispadias (1) or buried penis (18) were collected between November 2011 and September 2013. Tissue samples from 79 children undergoing circumcision for nonmedical reasons served as controls. All samples were stained with smooth muscle actin and analyzed by the same pathologist, who was blinded to indication for surgery. Chi-square and Fisher exact tests were applied.Results: Three different dartos tissue patterns were observed. Pattern I (normal) consisted of smooth muscle fibers of dartos tissue organized in a parallel configuration i...
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
赘婿应助YJ888采纳,获得10
1秒前
surong发布了新的文献求助10
2秒前
Shelby发布了新的文献求助10
2秒前
dyc238100发布了新的文献求助10
3秒前
树精发布了新的文献求助10
3秒前
liii发布了新的文献求助10
3秒前
3秒前
火柴盒完成签到,获得积分10
4秒前
如此这般发布了新的文献求助10
4秒前
5秒前
5秒前
6秒前
幸福大白发布了新的文献求助30
7秒前
Akitten关注了科研通微信公众号
7秒前
7秒前
闾丘剑封发布了新的文献求助10
9秒前
天天快乐应助Shelby采纳,获得10
9秒前
9秒前
华仔应助xn201120采纳,获得10
10秒前
木子李发布了新的文献求助10
10秒前
搬砖小土妞完成签到,获得积分20
11秒前
李星发布了新的文献求助10
12秒前
13秒前
13秒前
小哈发布了新的文献求助10
14秒前
15秒前
科研通AI5应助xielunwen采纳,获得10
15秒前
Tireastani应助Jack采纳,获得10
16秒前
Shelby完成签到,获得积分10
16秒前
会飞的扁担完成签到,获得积分10
16秒前
17秒前
幸福大白发布了新的文献求助30
18秒前
Leoniko发布了新的文献求助10
18秒前
18秒前
碧蓝邪欢完成签到,获得积分10
21秒前
小二郎应助YUMI采纳,获得10
21秒前
科研通AI2S应助不回首采纳,获得10
21秒前
听话的亦瑶应助不回首采纳,获得10
21秒前
谢许杯商应助不回首采纳,获得10
21秒前
慕青应助不回首采纳,获得30
21秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989510
求助须知:如何正确求助?哪些是违规求助? 3531756
关于积分的说明 11254536
捐赠科研通 3270255
什么是DOI,文献DOI怎么找? 1804947
邀请新用户注册赠送积分活动 882113
科研通“疑难数据库(出版商)”最低求助积分说明 809176