Solvent‐Free Synthesis of 3‐Amino‐2,4‐dicarbonitrile‐5‐methylbiphenyl by a Grinding Method

Abstract A convenient, environmentally friendly, and solvent‐free procedure has been developed for the synthesis of 3‐amino‐2,4‐dicarbonitrile‐5‐methylbiphenyl derivatives. Compared with the classical reaction condition, this new synthetic method has the advantages of excellent yields, easy setup, mild reaction conditions, and environmental friendlines.