Recent progress in metal–organic frameworks-based materials toward surface-enhanced Raman spectroscopy

The design and fabrication of novel and robust surface enhanced Raman spectroscopy (SERS) substrate are crucial for the widespread application of SERS technique in the fields of chemistry, biology, and environmental science. Recently, metal organic framework (MOF) material has emerged as attractive material with many unique properties such as high porosity, tunable structure, and rich functionalities. With the help of MOF material, MOF-based SERS substrate can show high sensitivity, excellent selectivity and outstanding stability. Herein, we have reviewed the latest research progress of MOF-based SERS substrate. We mainly focus on the design principles for MOF-based SERS substrates according to the roles of MOF material. Then the recent applications of MOF-based SERS substrates have been summarized. Finally, the future challenges and potential opportunities in the development of MOF-based SERS substrates are discussed.