基因分型
炎症性肠病
炎症性肠病
医学
计算生物学
生物
基因型
遗传学
内科学
基因
疾病
作者
Sare Verstockt,Laurens Hannes,Deborah Jans,Stephanie Deman,Erika Souche,Ilse van der Werf,Liv Vandermeulen,Triana Lobatón,Debby Laukens,Bram Verstockt,Jeroen Van Houdt,Alexander Hoischen,Séverine Vermeire,Isabelle Cleynen
摘要
Inflammatory bowel diseases (IBD) are polygenic, with many genetic variants contributing to disease risk. Knowing the genotype of specific variants or calculating a combined genetic risk score benefits translational and functional research. To address this, we developed MIP4IBD, a flexible and cost-effective genotyping-by-sequencing assay using molecular inversion probes (MIPs).
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