鲍曼不动杆菌
生物膜
抗生素
毒力
微生物学
病菌
不动杆菌
重症监护医学
医学
传输(电信)
生物
细菌
铜绿假单胞菌
基因
生物化学
遗传学
电气工程
工程类
作者
Seetha Lakshmi Rajangam,Manoj Kumar Narasimhan
出处
期刊:Future Microbiology
[Future Medicine]
日期:2024-04-29
卷期号:19 (10): 941-961
被引量:3
标识
DOI:10.2217/fmb-2023-0263
摘要
A higher prevalence of Acinetobacter baumannii infections and mortality rate has been reported recently in hospital-acquired infections (HAI). The biofilm-forming capability of A. baumannii makes it an extremely dangerous pathogen, especially in device-associated hospital-acquired infections (DA-HAI), thereby it resists the penetration of antibiotics. Further, the transmission of the SARS-CoV-2 virus was exacerbated in DA-HAI during the epidemic. This review specifically examines the complex interconnections between several components and genes that play a role in the biofilm formation and the development of infections. The current review provides insights into innovative treatments and therapeutic approaches to combat A. baumannii biofilm-related infections, thereby ultimately improving patient outcomes and reducing the burden of HAI.
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