姜黄素
机制(生物学)
股四头肌
药理学
再生(生物学)
医学
神经科学
化学
物理医学与康复
细胞生物学
生物
认识论
哲学
作者
Yingqi Hua,Ze-Qin Li,Jia‐ming Yang,Long Yi,Yan-Biao Zhong,Yi Wu,Maoyuan Wang
标识
DOI:10.1016/j.ejphar.2024.176910
摘要
Knee osteoarthritis (KOA) is a very common musculoskeletal disorder, and patients with KOA often exhibit significant quadriceps femoris muscle atrophy. It is well established that curcumin (CUR) exerts protective effects on skeletal muscle. However, the efficacy of CUR in treating KOA-induced quadriceps femoris muscle atrophy and its underlying mechanisms remain uncertain. In this study, we employed network pharmacology to investigate the mechanism by which CUR promotes regenerative repair of the quadriceps femoris muscle in rats with KOA.
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