医学
胃肠病学
内科学
普通外科
胰液
内窥镜检查
胰腺
出处
期刊:PubMed
日期:2023-10-31
卷期号:103 (40): 3174-3179
标识
DOI:10.3760/cma.j.cn112137-20230628-01089
摘要
The pancreaticobiliary junction (PBJ) stands as a pivotal "hub" where the bile and pancreatic ductsmerge, directing the flow rate and direction of bile and pancreatic juice. Benign pancreaticobiliary junction diseases(BPBJD) can lead to compromised outflow of bile and pancreatic secretions, resulting in elevated pressures within the bile and pancreatic ducts, causing ductal dilation, secretion stasis, and stone formation.Furthermore, BPBJD can shift the direction of bile and pancreatic juice, inducing pancreaticobiliary reflux, bile-pancreatic reflux, or enterobiliary reflux, thereby causing both acute and chronic inflammation and tumors in the biliopancreatic system. Owing to the unique anatomical position of the PBJ and the often intricate and elusive symptoms of benign diseases in this region, clinicians might mainly address standard biliary and pancreatic diseases, overlooking the primary issues associated with the PBJ.Such oversight can yield less-than-optimal clinical outcomes. In response to this, the Gallbladder-Preserving Surgery Committee, Endoscopy Specialist Branch of Chinese Medical Doctor Association and the editorial board of the National Medical Journal of China assembled renowned domestic experts from the fields of hepatobiliary and pancreatic surgery and digestive endoscopy. Drawing upon the latest domestic and international research findings, as well as the clinical expertise of specialists from related fields within China, they have collaboratively developed an expert consensus on the endoscopic diagnosis and treatment of BPBJD. The overarching aim is to propagate and standardize the diagnosis and treatment approaches for BPBJD.胆胰管汇合部是胆管与胰管相结合的“枢纽”部位,控制着胆汁和胰液的流速与流向。胆胰管汇合部良性疾病不仅会导致胆汁及胰液流出不畅,形成胆管和胰管高压,进一步引起胆胰管扩张、胆汁胰液淤积和结石,还会改变胆汁和胰液的流向,出现胰胆反流、胆胰反流或肠胆反流,引起胆胰系统的急慢性炎症和肿瘤。由于胆胰管汇合部解剖位置特殊,其良性疾病的临床症状复杂且隐蔽,临床医生多关注常见的胆胰疾病,而忽视了胆胰管汇合部的原发性疾病,从而导致临床治疗效果不理想。鉴于这种现状,中国医师协会内镜医师分会内镜微创保胆专业委员会组织了国内在肝胆胰外科和消化内镜领域的知名专家进行深入探讨,并结合了国内外的最新研究成果与国内相关领域专家的临床经验,进而制定出胆胰管汇合部良性疾病内镜诊治的专家共识,旨在推广和规范该疾病的诊断和治疗。.
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