摘要
Journal of the European Academy of Dermatology and VenereologyEarly View LETTER TO THE EDITOR Do psoriasis and atopic dermatitis affect erectile dysfunction? Insights from a Mendelian randomization study Nianzhou Yu, Nianzhou Yu orcid.org/0000-0001-6995-9840 Department of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha, Hunan, China National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaSearch for more papers by this authorYeye Guo, Yeye Guo Department of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha, Hunan, China National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaSearch for more papers by this authorShuang Zhao, Corresponding Author Shuang Zhao [email protected] Department of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha, Hunan, China National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China Correspondence Shuang Zhao and Xiang Chen, Department of Dermatology, Xiangya Hospital of Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan Province, China. Email: [email protected] and [email protected]Search for more papers by this authorXiang Chen, Corresponding Author Xiang Chen [email protected] orcid.org/0000-0001-8187-636X Department of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha, Hunan, China National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China Correspondence Shuang Zhao and Xiang Chen, Department of Dermatology, Xiangya Hospital of Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan Province, China. Email: [email protected] and [email protected]Search for more papers by this author Nianzhou Yu, Nianzhou Yu orcid.org/0000-0001-6995-9840 Department of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha, Hunan, China National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaSearch for more papers by this authorYeye Guo, Yeye Guo Department of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha, Hunan, China National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaSearch for more papers by this authorShuang Zhao, Corresponding Author Shuang Zhao [email protected] Department of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha, Hunan, China National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China Correspondence Shuang Zhao and Xiang Chen, Department of Dermatology, Xiangya Hospital of Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan Province, China. Email: [email protected] and [email protected]Search for more papers by this authorXiang Chen, Corresponding Author Xiang Chen [email protected] orcid.org/0000-0001-8187-636X Department of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha, Hunan, China National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China Correspondence Shuang Zhao and Xiang Chen, Department of Dermatology, Xiangya Hospital of Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan Province, China. Email: [email protected] and [email protected]Search for more papers by this author First published: 11 October 2023 https://doi.org/10.1111/jdv.19571Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. REFERENCES 1Hatzimouratidis K, Amar E, Eardley I, Giuliano F, Hatzichristou D, Montorsi F, et al. Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation. 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GWAS identifies risk locus for erectile dysfunction and implicates hypothalamic neurobiology and diabetes in etiology. Am J Hum Genet. 2019; 104: 157–163. 7Zhang C, Chinnappan M, Prestwood C, Edwards M, Artami M, Thompson B, et al. Interleukins 4 and 13 drive lipid abnormalities in skin cells through regulation of sex steroid hormone synthesis. Proc Natl Acad Sci U S A. 2021; 118: e2100749118. 8Li H, Xu W, Liu X, Wang T, Wang S, Liu J, et al. JAK2 deficiency improves erectile function in diabetic mice through attenuation of oxidative stress, apoptosis, and fibrosis. Andrology. 2021; 9: 1662–1671. 9Dowlatshahi E, Wakkee M, Arends L, Nijsten T. The prevalence and odds of depressive symptoms and clinical depression in psoriasis patients: a systematic review and meta-analysis. J Invest Dermatol. 2014; 134: 1542–1551. 10Cather J, Ryan C, Meeuwis K, Potts Bleakman A, Naegeli A, Edson-Heredia E, et al. Patients' perspectives on the impact of genital psoriasis: a qualitative study. 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