骨关节炎
关节软骨
间充质干细胞
移植
医学
软骨
干细胞
外科
病理
解剖
生物
替代医学
细胞生物学
出处
期刊:PubMed
日期:2024-05-07
卷期号:104 (17): 1445-1452
标识
DOI:10.3760/cma.j.cn112137-20231007-00664
摘要
The prevalence of articular cartilage injuries and osteoarthritis (OA) is high, affecting a wide range of individuals. The self-repair ability of cartilage tissue is poor, and once damaged, it will irreversibly progress to OA. Mesenchymal stem cells (MSCs) play an important role in the field of regenerative medicine and are considered one of the most promising seed cells for cartilage repair and regeneration. In this article, based on the latest clinical research findings from both domestic and international sources, the theoretical basis, treatment goals, significance, sources, characteristics, clinical implementation plans, and efficacy of using MSCs for the treatment of cartilage injuries or osteoarthritis are reviewed. The article also discusses the challenges faced and future directions that need to be addressed in the clinical application of MSCs.
科研通智能强力驱动
Strongly Powered by AbleSci AI