生物
癌相关成纤维细胞
快照（计算机存储）
肿瘤微环境
癌症研究
人口
细胞生物学
肿瘤细胞
计算机科学
操作系统
社会学
人口学
作者
Danielle Park,Erik Sahai,Antonio Rullan
出处
期刊：Cell
[Elsevier]
日期：2020-04-01
卷期号：181 (2): 486-486.e1
被引量：85
标识
DOI：10.1016/j.cell.2020.03.013
摘要
Cancer-associated fibroblasts (CAFs) are an integral component of the tumor microenvironment and have both tumor-promoting and tumor-suppressive functions. This SnapShot summarizes the origins of CAFs, their diverse functions, and how this relates to heterogeneity within the population. The suitability of targeting CAFs therapeutically is also discussed.
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