嗅觉缺失
2019年冠状病毒病(COVID-19)
严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)
2019-20冠状病毒爆发
医学
冠状病毒感染
肺炎
嗅觉减退
倍他科诺病毒
病毒学
内科学
爆发
传染病(医学专业)
疾病
作者
Timothée Klopfenstein,N’dri Juliette Kadiane-Oussou,L. Toko,P.-Y. Royer,Quentin Lepiller,Vincent Gendrin,Souheil Zayet
标识
DOI:10.1016/j.medmal.2020.04.006
摘要
Medical publications about anosmia with COVID-19 are scarce. We aimed to describe the prevalence and features of anosmia in COVID-19 patients.We retrospectively included COVID-19 patients with anosmia between March 1st and March 17th, 2020. We used SARS-CoV-2 real time PCR in respiratory samples to confirm the cases.Fifty-four of 114 patients (47%) with confirmed COVID-19 reported anosmia. Mean age of the 54 patients was 47 (±16) years; 67% were females and 37% were hospitalised. The median Charlson comorbidity index was 0.70 (±1.6 [0-7]). Forty-six patients (85%) had dysgeusia and 28% presented with pneumonia. Anosmia began 4.4 (±1.9 [1-8]) days after infection onset. The mean duration of anosmia was 8.9 (±6.3 [1-21]) days and 98% of patients recovered within 28 days.Anosmia was present in half of our European COVID-19 patients and was often associated with dysgeusia.
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