Association of Body Weight Change and Fluid Balance With Extubation Failure in Intensive Care Unit Patients: A Single-Center Observational Study

医学 优势比 置信区间 重症监护室 机械通风 麻醉 平衡(能力) 逻辑回归 内科学 物理疗法
作者
Shota Maezawa,Daisuke Kudo,Noriko Miyagawa,Satoshi Yamanouchi,Shigeki Kushimoto
出处
期刊:Journal of Intensive Care Medicine [SAGE]
卷期号:36 (2): 175-181 被引量:19
标识
DOI:10.1177/0885066619887694
摘要

To elucidate whether fluid balance and body weight change are associated with failed planned extubation.Patients who received invasive mechanical ventilation for over 24 hours were enrolled and divided into extubation success and extubation failure groups. Fluid balance and body weight fluctuation within 24 and 48 hours before extubation and from admission to planned extubation were calculated. The primary outcome was extubation failure (ie, all-cause reintubation within 72 hours). The association of extubation failure with fluid balance and body weight change was assessed via logistic regression analysis.Extubation failure occurred in 12(7.4%)/161 patients. The extubation success group had a significantly lower fluid balance within 24 hours before extubation than did the extubation failure group (-276 mL [-1111 to 456] vs 1217 mL [503 to 1875], P = .002). However, fluid balance within 48 hours before extubation, cumulative fluid balance, and body weight change were not significantly different between the 2 groups. The sensitivity and specificity of water balance +1000 mL within 24 hours before extubation for the extubation failure group were 0.54 and 0.84, respectively, based on the receiver operating characteristic curve. Logistic regression analysis showed that fluid balance within 24 hours before extubation was associated with extubation failure (odds ratio: 22.9, 95% confidence interval: 4.1-128.4).A larger fluid balance within 24 hours before extubation is associated with extubation failure. Thus, fluid balance may be a good indicator of extubation outcome.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
李爱国应助少少少采纳,获得10
1秒前
吹泡泡的红豆完成签到 ,获得积分10
1秒前
2秒前
Lr完成签到,获得积分10
2秒前
2秒前
许可可仔儿完成签到,获得积分10
3秒前
36456657应助落后的夜阑采纳,获得10
3秒前
不灭完成签到,获得积分10
3秒前
YunZeng发布了新的文献求助10
3秒前
3秒前
4秒前
调研昵称发布了新的文献求助10
4秒前
研友_LwbGg8完成签到,获得积分10
4秒前
FashionBoy应助机智达采纳,获得10
4秒前
热闹的冬天完成签到,获得积分10
4秒前
5秒前
5秒前
panpan完成签到,获得积分10
5秒前
6秒前
6秒前
zero完成签到 ,获得积分10
7秒前
哈哈哈发布了新的文献求助10
7秒前
慕青应助哒哒李采纳,获得10
7秒前
研友_LwbGg8发布了新的文献求助10
8秒前
Lei发布了新的文献求助10
8秒前
zxx5313491完成签到,获得积分20
9秒前
jun完成签到 ,获得积分10
9秒前
ZWL001完成签到,获得积分10
9秒前
10秒前
肖志勇发布了新的文献求助10
11秒前
11秒前
JamesOliver应助swordlee采纳,获得10
12秒前
福尔摩云完成签到,获得积分10
13秒前
贾败发布了新的文献求助30
13秒前
NexusExplorer应助ZWL001采纳,获得10
13秒前
rekha完成签到,获得积分10
14秒前
zzzq完成签到,获得积分10
14秒前
老鼠爱吃fish完成签到,获得积分10
15秒前
星燃完成签到,获得积分10
15秒前
loong发布了新的文献求助10
16秒前
高分求助中
Production Logging: Theoretical and Interpretive Elements 2700
Mechanistic Modeling of Gas-Liquid Two-Phase Flow in Pipes 2500
Kelsen’s Legacy: Legal Normativity, International Law and Democracy 1000
Handbook on Inequality and Social Capital 800
Conference Record, IAS Annual Meeting 1977 610
Interest Rate Modeling. Volume 3: Products and Risk Management 600
Interest Rate Modeling. Volume 2: Term Structure Models 600
热门求助领域 (近24小时)
化学 材料科学 生物 医学 工程类 有机化学 生物化学 物理 纳米技术 计算机科学 内科学 化学工程 复合材料 基因 遗传学 物理化学 催化作用 量子力学 光电子学 冶金
热门帖子
关注 科研通微信公众号,转发送积分 3546536
求助须知:如何正确求助?哪些是违规求助? 3123667
关于积分的说明 9356348
捐赠科研通 2822331
什么是DOI,文献DOI怎么找? 1551314
邀请新用户注册赠送积分活动 723326
科研通“疑难数据库(出版商)”最低求助积分说明 713699