医学
放射科
肺
活检
腺癌
外围设备
肺癌
计算机断层摄影术
肺活检
病理
癌症
内科学
作者
Calogero Porrello,Roberto Lo Gullo,Carola Maria Gagliardo,Antonino Vaglica,M Palazzolo,F Giangregorio,D Iadicola,Andrea Catanzaro,Grégorio Scerrino,Felice Lo Faso,F Carini,Giovanni Tomasello
出处
期刊:Future Oncology
[Future Medicine]
日期:2019-10-09
卷期号:16 (sup16): 27-32
被引量:8
标识
DOI:10.2217/fon-2019-0076
摘要
Aim: The present study aimed to demonstrate that computed tomography-guided transthoracic needle biopsy (TTNB) is a safe procedure that gives a more accurate pre-operative tissue diagnosis for peripheral lung nodules than transthoracic needle aspiration, obtaining suitable samples for molecular test in lung adenocarcinomas. Patients & methods: Between December 2016 and March 2018 at Thoracic Surgery Department of the University of Palermo – Policlinico Paolo Giaccone hospital, TTNB was performed in 42 patients with computed tomography-detected peripheral lung nodules >10 mm, using 16–18-Gauge Tru-Cut needles. Results: With TTNB, we have estimated an accuracy for tissue diagnosis of 97.6%. At the molecular test, EGFR overexpression and ALK mutation resulted positive for 12/23 patients with lung adenocarcinoma. Conclusion: TTNB has showed a low rate of complications and it is adoptable as standard diagnostic procedure for peripheral lung nodules.
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