The epidemiological survey of quality of life in patients with Thyroid-associated ophthalmopathy

Objective To evaluate the Thyroid-associated ophthalmopathy patients' quality of life using the current internationally accepted Graves' Ophthalmolopathy Quality of Life questionnaire (GO-QOL).Methods Collected in 75 patients with the thyroid-associated ophthalmopathy and 75 cases normal control group.Application GO-QOL to compare the differences in quality of life,analysis the factors caused reducing quality of life in the Thyroid-associated ophthalmopathy.Results Thyroid associated ophthalmopathy patient group and control group's quality of life scores were significantly different,and visual function and psychosocial scores in the thyroid-associated ophthalmopathy were all lower than the normal control group (P ＜0.001).There were no significant differences between visual function scores in patients of differcnt gender (0.06,0.07),the 50-year-older group's the functional scores and psychosocial scores were statistically significant differences than the other two groups (0.01,0.02,0.008,0.005).There was no significant difference between visual function scores in patients of different gender (0.06).The social psychology of women scored significantly lower than men's,and the difference was statistically significant (0.008).Exophthalmos and lid retraction group score and visual function scores had no significant difference in social psychology scores (0.06,0.08),the diplopia group and the other two groups in visual function and psychosocial scores had significant statistical difference (0.001,0.03; 0.004,0.01); two groups of patients with eye disease rating score of visual function and no difference in social psychology (0.06,0.09).Conclusions The quality of life in the Thyroid-associated ophthalmopathy is lower than the normal population.The major affect factors include age,gender and diplopia. Key words: Thyroid associated ophthalmopathy; Quality of life; Graves' Ophthalmolopathy Quality of Life questionnaire (GO-QOL); Epidemiological survey