药物重新定位
重新调整用途
药物发现
小檗碱
药品
计算机科学
斯科普斯
糖尿病
药理学
医学
梅德林
生物信息学
工程类
生物
内分泌学
生物化学
废物管理
作者
Sweta Mohanty,Md. Harun Al Rashid,Chandana Mohanty,Swati Swayamsiddha
标识
DOI:10.1016/j.dsx.2021.06.017
摘要
Objectives are to explore recent advances in discovery of new antidiabetic agents using repurposing strategies and to discuss modern technologies used for drug repurposing highlighting diabetic specific web portal.Recent literature were studied and analyzed from various sources such as Scopus, PubMed, and IEEE Xplore databases.Drugs like Niclosamideethanolamine, Methazolamide, Diacerein, Berberine, Clobetasol, etc. with possibility of repurposing to curb diabetes can be potential late-stage clinical candidates, providing access to information on pharmacology, formulation, and probable toxicity if any.With collaboration of artificial intelligence (AI) with pharmacology, the efficiency of drug repurposing can improve significantly.
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