生物
动力素
胞质分裂
机制(生物学)
内吞作用
细胞器生物发生
细胞生物学
功能(生物学)
生物发生
细胞器
细胞骨架
计算生物学
遗传学
细胞
细胞分裂
基因
哲学
认识论
作者
John R. Jimah,Jenny E. Hinshaw
标识
DOI:10.1016/j.tcb.2018.11.003
摘要
Dynamin superfamily proteins (DSPs) mediate membrane fission and fusion necessary for endocytosis, organelle biogenesis and maintenance, as well as for bacterial cytokinesis. They also function in the innate immune response to pathogens and in organizing the cytoskeleton. In this review, we summarize the current understanding of the molecular mechanism of DSPs, with emphasis on the structural basis of function. Studies from the past decade on the structure and mechanism of DSPs enable comparative analysis of shared mechanisms and unique features of this protein family.
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