化学
氢胺化
铱
氧化加成
氢化物
胺化
烯烃纤维
配体(生物化学)
氨
单体
催化作用
光化学
药物化学
无机化学
有机化学
金属
生物化学
聚合物
受体
作者
Jing Zhao,Alan S. Goldman,John F. Hartwig
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2005-02-18
卷期号:307 (5712): 1080-1082
被引量:413
标识
DOI:10.1126/science.1109389
摘要
The insertion of an iridium complex into an N-H bond in ammonia leads to a stable monomeric amido hydride complex in solution at room temperature. This reaction advances the transition-metal coordination chemistry of ammonia beyond its role for more than a century as an ancillary ligand. The precursor for this insertion reaction is an iridium(I) olefin complex with an aliphatic ligand containing one carbon and two phosphorus donor atoms. Kinetic and isotopic labeling studies indicate that olefin dissociates to give a 14-electron iridium(I) fragment, which then reacts with ammonia. This cleavage of the N-H bond under neutral conditions provides a foundation on which to develop future mild catalytic transformations of ammonia, such as olefin hydroamination and arene oxidative amination.
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