丝胶
化学
共价键
抗氧化剂
对苯二酚
邻苯三酚
生物相容性
有机化学
多酚
丝绸
材料科学
复合材料
作者
Adil Omar,Amina Arken,Haji Akber Aisa,Yanhua Gao
标识
DOI:10.1016/j.procbio.2022.03.008
摘要
Sericin, as an inexpensive byproduct of the silk industry, has drawn increasing attention due to its good biocompatibility and various bioactivities. Covalent interactions between proteins and phenolic compounds are ubiquitous and can affect the functional properties of proteins, but little is known about the interactions between sericin and phenolic compounds. In our research, hydroquinone and pyrogallol were selected as model phenolic compounds to investigate the interaction between sericin and phenolic compounds. UV spectroscopy and SEC-HPLC confirmed that sericin and oxidized phenolic compounds formed conjugates, which were primarily the result of covalent interactions. The covalent binding of phenolic compounds changed the secondary structure and thermal behavior of sericin and increased its surface hydrophobicity. The covalent interaction had a positive effect on the emulsifying activity of sericin. Likewise, the antioxidant activity and anti-inflammatory activity of sericin were enhanced in the presence of phenolic compounds. Sericin-phenolic conjugates would be used as multifunctional ingredients in cosmetics, food, and other industries due to their improved emulsifying, antioxidant, and anti-inflammatory properties.
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