Three new phloroglucinol derivatives from the aerial parts of Pogostemon auricularius and their cytotoxic activity

Pogostemonons A–C (1–3), three new phloroglucinol derivatives were isolated from the aerial parts of Pogostemon auricularius (L.) Hassk. Their chemical structures were established by 1D, 2D NMR and HRESIMS data. These compounds showed weak to moderate growth inhibitory activities against lung adenocarcinoma (LU-1), oral epidermoid carcinoma (KB), liver hepatocellular carcinoma (Hep-G2), colon adenocarcinoma (SW-480), and gastric adenocarcinoma (AGS) cell lines with IC50 values ranging from 39.80 ± 4.39 to 98.32 ± 8.94 μg/mL.