医学
动脉硬化
脉冲波速
呼吸障碍指数
内科学
血压
心脏病学
活动记录
睡眠呼吸暂停
睡眠(系统调用)
阻塞性睡眠呼吸暂停
物理疗法
多导睡眠图
呼吸暂停
昼夜节律
计算机科学
操作系统
作者
Lorenna F. Cunha,Ronaldo B. Santos,Soraya Giatti,Barbara K. Parise,Aline N. Aielo,Wagner A. Silva,Samilly Evangelista Souza,Luiz Aparecido Bortolotto,Paulo A Lotufo,Isabela M. Benseñor,Luciano F. Drager
标识
DOI:10.1177/00033197231193618
摘要
Increased arterial stiffness is independently associated with cardiovascular risk. Obstructive sleep apnea (OSA) and sleep duration (SDUR) may contribute to increased arterial stiffness, but it is unclear whether this association is modulated by gender. We aimed to evaluate the potential impact of gender in modulating the association of OSA and SDUR with arterial stiffness. Participants from the ELSA-Brasil study performed sleep assessments with portable polygraph to define OSA severity and SDUR by 1-week wrist actigraphy. Pulse wave velocity (PWV) was measured using a standard technique without access to the sleep data. We studied 1863 participants (42.2% male, age: 49±8 years, respiratory disturbance index (RDI): 9.9 (4.5–19.4) events/h, SDUR: 6.5 (5.9–7.1) hours, mean PWV: 7.3 ± 1.2 m/s). We found that men had higher PWV, higher frequency of diabetes, and higher blood pressure when compared to women. The regression analysis showed an independent association between increased RDI and PWV in men (ß: 0.007; 95% CI: 0.001–0.012), but not in women. In contrast, an independent association between SDUR and increased arterial stiffness was observed only in women (ß: 0.068; 95% CI: 0.002–0.134). In conclusion, the association of sleep disorders with arterial stiffness showed a distinct gender pattern depending on the sleep variable studied.
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