Proximal serrated polyp detection rate and post-colonoscopy colorectal cancer: the missing link

Colorectal cancer (CRC) is among the most prevalent forms of cancer worldwide and is responsible for a substantial proportion of cancer-related deaths [1]. Colonoscopy with polypectomy of all relevant lesions is vital for the prevention of CRC. Unfortunately, up to 8 % of all CRCs occur after colonoscopy, also demonstrating its limitations [2]. The literature shows that the majority of these so-called post-colonoscopy CRCs (PCCRCs) are due to missed or incompletely resected lesions [3]. Therefore, improving colonoscopy quality seems key to decreasing the incidence of PCCRC.