Visible light metallaphotoredox catalysis in the late-stage functionalization of pharmaceutically potent compounds
化学
表面改性
催化作用
组合化学
阶段(地层学)
有机化学
物理化学
生物
古生物学
作者
Praveen P. Singh,Pravin K. Singh,Vishal Srivastava
出处
期刊:Organic chemistry frontiers [The Royal Society of Chemistry] 日期:2022-11-08卷期号:10 (1): 216-236被引量:41
标识
DOI:10.1039/d2qo01582j
摘要
The late stage functionalization (LSF) is a distinctive approach for accelerating the discovery of structure–activity relationships (SARs) and optimising ADME (absorption, distribution, metabolism, and excretion) profiles.